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GLP-1 reconstitution calculator

If you were given a powder vial with written mixing instructions, this shows the arithmetic: the strength those amounts come to, and what a prescribed dose is in units.

No FDA-approved GLP-1 comes as a powder you mix

It shows the arithmetic on the amounts you were given. It won’t tell you how much liquid to add.

Read what FDA says
What does your vial say it contains?
mg

Copy it from the vial. This is the whole vial, not your dose.

mL

Use the amount in your pharmacist’s written instructions. This tool never suggests one.

mg

Enter the dose on your prescription. This tool can’t tell you what it should be.

For U-100 syringes: 100 units = 1 mL.

Syringe size

For FDA’s 28-day date. An earlier printed deadline still applies.

Use the earlier applicable date. Dates do not establish that a vial can be used.

Your result stays hidden

It appears when the required fields are filled in and you’ve ticked the box. The box starts empty each time, and nothing is saved.

How this works

The math

How the arithmetic works

strength in mg/mL = powder in mg ÷ liquid in mLmL for a dose = dose in mg ÷ strength in mg/mLunits = mL × 100 (U-100 only)

For example, 20 mg with 2 mL added is 10 mg/mL, and a 5 mg dose at that strength is 0.5 mL, or 50 units. The same 5 mg at 5 mg/mL is 100 units, which is why the strength has to be right before anything else.

This assumes the powder adds no volume to the liquid. That isn’t always true, and only your pharmacist can say for your vial.

What the label shows
Mixing a powder
No label for these medicines describes it. Each comes as a ready-made solution.2345
Compounded powder
FDA says compounded drugs “pose a higher risk” than approved ones, and should only be used for patients whose medical needs can’t be met by an available FDA-approved drug.6
Vials sold “for research”
FDA says these are illegally sold, unapproved and of unknown quality, and urges people not to buy them.1
Salt forms
FDA says semaglutide sodium and semaglutide acetate are different active ingredients from the approved medicines, and that it isn’t aware of a lawful basis for compounding with them.1
After first use
For compounded multiple-dose vials, FDA says to discard within 28 days after first use, and to use a new, sterile needle and syringe for each dose.1
This page
It does arithmetic. It doesn’t teach mixing, and it can’t tell you whether a powder is sterile, what strength it really is or whether you should use it.
Dates do not establish usability
An earlier printed expiry or beyond-use date, storage conditions and the vial’s own instructions can shorten a deadline. This arithmetic cannot establish that a vial can be used. Check with your pharmacist first.
Four weekly doses
The count uses days 0, 7, 14 and 21, and excludes a fifth dose on day 28. Discard on day 28 at the latest, or an earlier applicable deadline.
Before you act on this

The FDA reports include people who meant to draw 5 units and drew 50, and one who searched online for advice and took five times their dose.6 Say your number out loud and look at the syringe before you inject.

Took more than you were prescribed? Call your prescriber or pharmacist now. In the US, Poison Help is 1-800-222-1222. Severe vomiting, severe nausea or signs of low blood sugar need urgent care.

Something went wrong, or a vial looks or acts wrong? Tell your prescriber. In the US, you can also report it to FDA’s MedWatch program.1

Always follow your doctor’s or prescriber’s advice and guidance. Talk to your prescriber before changing your dose.

Read this first

No FDA-approved GLP-1 comes as a powder you mix

  • Zepbound, Mounjaro, Wegovy and Ozempic injections come as ready-made solutions, and none of their labels describes mixing.2345 FDA says compounded drugs aren’t FDA approved, and that it doesn’t review them for safety, effectiveness or quality before they’re sold.1
  • If your vial says “for research purposes” or “not for human consumption”: FDA says these products are sold illegally, are of unknown quality and may be harmful, and it urges people not to buy them.1 No arithmetic can tell you what’s in a vial.
  • A wrong strength makes every dose from that vial wrong. FDA has adverse event reports, some needing hospital care, that may be related to dosing errors with compounded semaglutide. Most described people drawing too much from a vial, five to 20 times more than the intended dose.6

For information only, not medical advice. Verify results with your healthcare provider; Onederland accepts no liability for use of these tools.

  • Runs on this device. Nothing you type is sent anywhere.
  • Every figure names its source, below.
  • Education, not medical advice. Your prescriber comes first.
Sources

Sources

  1. FDA: concerns with unapproved GLP-1 medicines, October 1, 2026. fda.gov
  2. Zepbound (tirzepatide) injection, US prescribing information, revised 08/2026. accessdata.fda.gov
  3. Mounjaro (tirzepatide) injection, US prescribing information, revised 08/2026. accessdata.fda.gov
  4. Wegovy (semaglutide) injection and tablets, US prescribing information, revised 06/2026. accessdata.fda.gov
  5. Ozempic (semaglutide) injection, US prescribing information, revised 05/2026. accessdata.fda.gov
  6. FDA: dosing errors with compounded injectable semaglutide, July 26, 2024. fda.gov

Label sources last checked on October 30, 2026. Onederland summarizes them; your prescriber and the full prescribing information come first.

About powder vials

How much water do I add?

This tool can’t tell you, and won’t suggest an amount. It has to come from the pharmacist who dispensed the vial, in writing. If you don’t have that, ask before you do anything else.

Does this make mixing safe?

No. Correct arithmetic can’t make up for a powder of unknown quality, a wrong amount on the vial, or contamination while mixing.

How long is a mixed vial good for?

For a compounded multiple-dose vial, FDA says to discard within 28 days after first use, even if medicine remains and even if the instructions you were given say longer.

Why isn’t there a printable vial label?

A label from a website could look like one from a pharmacy, and a wrong number on it would repeat with every dose. You can print this page to take to your pharmacist.

Published by Micktron LLC · Sources checked October 30, 2026

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