‹ All tools

GLP-1 dose schedule: the steps on each label

Every medicine starts low and steps up.

Talk to your prescriber before changing your dose. This page can’t tell you which step is right for you, or when to move.

Your numbers will appear here

Enter your own details to see the arithmetic. The examples below are made up.

How this works

The math

Why medicines step up

Labels start low and go up slowly to reduce the risk of stomach and gut side effects. The starting dose is usually for getting used to the medicine, not for long-term use.1

A label gives the least time at a step. It doesn’t say you have to move up. If a dose is hard to tolerate, labels tell prescribers to consider a slower pace or a lower dose.12

What the label shows

These are adult label tables. Children and adolescents can have different dose limits.

US

Wegovy2

DoseMinimum timeRole on the label
0.25 mg4 weeksStarting dose
0.5 mg4 weeksStep
1 mg4 weeksStep
1.7 mg4 weeksMaintenance
2.4 mg4 weeksMaintenance
7.2 mgOngoingHighest dose

The 7.2 mg dose is only for adult weight reduction, after tolerating 2.4 mg for at least 4 weeks and when further weight reduction is clinically indicated. For cardiovascular risk reduction, maintenance is 2.4 mg (recommended) or 1.7 mg weekly. For noncirrhotic MASH with moderate to advanced fibrosis, maintenance is 2.4 mg weekly; 1.7 mg may be used if 2.4 mg is not tolerated.2

Ozempic3

DoseMinimum timeRole on the label
0.25 mg4 weeksStarting dose
0.5 mg4 weeksMaintenance
1 mg4 weeksMaintenance
2 mgOngoingHighest dose

This label is for type 2 diabetes. These are not weight-loss dose steps.

These are glycemic-control steps. The US label also covers cardiovascular risk reduction in adults with type 2 diabetes and established cardiovascular disease, and kidney and cardiovascular risk reduction in adults with type 2 diabetes and chronic kidney disease. For the kidney indication, maintenance is 1 mg weekly after at least 4 weeks on 0.5 mg.3

Zepbound1

DoseMinimum timeRole on the label
2.5 mg4 weeksStarting dose
5 mg4 weeksMaintenance
7.5 mg4 weeksStep
10 mg4 weeksMaintenance
12.5 mg4 weeksStep
15 mgOngoingHighest dose

The US label lists 5 mg, 10 mg, or 15 mg once weekly as maintenance doses for weight reduction and long-term maintenance. For obstructive sleep apnea, the maintenance doses are 10 mg or 15 mg once weekly. This table does not choose a dose.1

Mounjaro4

DoseMinimum timeRole on the label
2.5 mg4 weeksStarting dose
5 mg4 weeksStep
7.5 mg4 weeksStep
10 mg4 weeksStep
12.5 mg4 weeksStep
15 mgOngoingHighest dose

This label is for type 2 diabetes. These are not weight-loss dose steps.

The US label covers glycemic control and cardiovascular risk reduction in eligible adults with type 2 diabetes. Dose increases are based on a need for additional glycemic control; there is no separate cardiovascular dose schedule.4

Wegovy pill2

DoseMinimum timeRole on the label
1.5 mg30 daysStarting dose
4 mg30 daysStep
9 mg30 daysStep
25 mgOngoingMaintenance

The US tablet schedule applies to weight reduction and cardiovascular risk reduction in eligible adults, with 25 mg daily as maintenance. The MASH indication is for the injection.2

Ozempic pill5

DoseMinimum timeRole on the label
1.5 mg30 daysStarting dose
4 mg30 daysMaintenance
9 mgOngoingHighest dose

This label is for type 2 diabetes. These are not weight-loss dose steps.

The US tablet label also covers cardiovascular risk reduction in adults with type 2 diabetes at high cardiovascular risk. It uses the same schedule, with increases based on a need for additional glycemic control.5

Rybelsus5

DoseMinimum timeRole on the label
3 mg30 daysStarting dose
7 mg30 daysMaintenance
14 mgOngoingHighest dose

This label is for type 2 diabetes. These are not weight-loss dose steps.

The US tablet label also covers cardiovascular risk reduction in adults with type 2 diabetes at high cardiovascular risk. It uses the same schedule, with increases based on a need for additional glycemic control.5

Foundayo6

DoseMinimum timeRole on the label
0.8 mg30 daysStarting dose
2.5 mg30 daysStep
5.5 mg30 daysStep
9 mg30 daysStep
14.5 mg30 daysStep
17.2 mgOngoingHighest dose

EU

Wegovy7

DoseMinimum timeRole on the label
0.25 mg4 weeksStarting dose
0.5 mg4 weeksStep
1 mg4 weeksStep
1.7 mg4 weeksStep
2.4 mg4 weeksMaintenance
7.2 mgOngoingMaintenance

For adults, the EU label permits the 7.2 mg maintenance dose only when BMI was at least 30 at treatment initiation, after at least 4 weeks on 2.4 mg. This table does not choose a dose.7

Ozempic8

DoseMinimum timeRole on the label
0.25 mg4 weeksStarting dose
0.5 mg4 weeksMaintenance
1 mg4 weeksMaintenance
2 mgOngoingHighest dose

This label is for type 2 diabetes. These are not weight-loss dose steps.

Mounjaro9

DoseMinimum timeRole on the label
2.5 mg4 weeksStarting dose
5 mg4 weeksMaintenance
7.5 mg4 weeksStep
10 mg4 weeksMaintenance
12.5 mg4 weeksStep
15 mgOngoingMaintenance

The EU label covers type 2 diabetes and weight management. The adult schedule is shared, with 5 mg, 10 mg or 15 mg weekly as maintenance doses.9

Wegovy pill7

DoseMinimum timeRole on the label
1.5 mg4 weeksStarting dose
4 mg4 weeksStep
9 mg4 weeksStep
25 mgOngoingMaintenance

Rybelsus10

Label schedule starting at 1.5 mg

DoseMinimum timeRole on the label
1.5 mg1 monthStarting dose
4 mg1 monthMaintenance
9 mg1 monthMaintenance
25 mg1 monthMaintenance
50 mgOngoingMaintenance

Label schedule starting at 3 mg

These are separate label schedules, not a milligram-for-milligram conversion. The current EU product information describes the 25 mg and 50 mg tablets as oval.10

DoseMinimum timeRole on the label
3 mg1 monthStarting dose
7 mg1 monthMaintenance
14 mg1 monthMaintenance
25 mg1 monthMaintenance
50 mgOngoingMaintenance

This label is for type 2 diabetes. These are not weight-loss dose steps.

Japan

Wegovy11

DoseMinimum timeRole on the label
0.25 mg4 weeksStarting dose
0.5 mg4 weeksStep
1 mg4 weeksStep
1.7 mg4 weeksStep
2.4 mgOngoingMaintenance

The Japanese label covers obesity and noncirrhotic MASH with moderate or advanced fibrosis. Both use the same adult escalation to 2.4 mg weekly; the dose may be reduced according to the patient’s condition.11

Ozempic12

DoseMinimum timeRole on the label
0.25 mg4 weeksStarting dose
0.5 mg4 weeksMaintenance
1 mgOngoingHighest dose

This label is for type 2 diabetes. These are not weight-loss dose steps.

Zepbound13

DoseMinimum timeRole on the label
2.5 mg4 weeksStarting dose
5 mg4 weeksMaintenance
7.5 mg4 weeksStep
10 mg4 weeksMaintenance
12.5 mg4 weeksStep
15 mgOngoingHighest dose

For obesity, the Japanese label describes 10 mg as the usual dose after escalation, with 5 mg or up to 15 mg according to the patient’s condition. The steps here do not choose a dose for you.13

For moderate to severe obstructive sleep apnea, the Japanese label uses escalation to 15 mg weekly, with adjustment within 10–15 mg if not tolerated. The obesity dose description above is not the sleep-apnea schedule.13

Mounjaro14

DoseMinimum timeRole on the label
2.5 mg4 weeksStarting dose
5 mg4 weeksMaintenance
7.5 mg4 weeksStep
10 mg4 weeksStep
12.5 mg4 weeksStep
15 mgOngoingHighest dose

This label is for type 2 diabetes. These are not weight-loss dose steps.

Rybelsus15

DoseMinimum timeRole on the label
3 mg4 weeksStarting dose
7 mg4 weeksMaintenance
14 mgOngoingHighest dose

This label is for type 2 diabetes. These are not weight-loss dose steps.

Before you act on this

Talk to your prescriber before changing your dose. This page can’t tell you which step is right for you, or when to move.

Always follow your doctor’s or prescriber’s advice and guidance. Talk to your prescriber before changing your dose.

For information only, not medical advice. Verify results with your healthcare provider; Onederland accepts no liability for use of these tools.

  • Runs on this device. Nothing you type is sent anywhere.
  • Every figure names its source, below.
  • Education, not medical advice. Your prescriber comes first.
Sources

Sources

  1. Zepbound (tirzepatide) injection, US prescribing information, revised 08/2026. accessdata.fda.gov
  2. Wegovy (semaglutide) injection and tablets, US prescribing information, revised 06/2026. accessdata.fda.gov
  3. Ozempic (semaglutide) injection, US prescribing information, revised 05/2026. accessdata.fda.gov
  4. Mounjaro (tirzepatide) injection, US prescribing information, revised 08/2026. accessdata.fda.gov
  5. Rybelsus and Ozempic (semaglutide) tablets, US prescribing information, revised 01/2026. accessdata.fda.gov
  6. Foundayo (orforglipron) tablets, US prescribing information, revised 07/2026. dailymed.nlm.nih.gov
  7. EU product information for semaglutide for weight management (tablets: summary of product characteristics, section 4.2), updated 21 September 2026. ema.europa.eu
  8. EU product information: injectable semaglutide for type 2 diabetes. ema.europa.eu
  9. EU product information: tirzepatide. ema.europa.eu
  10. EU product information: oral semaglutide for type 2 diabetes. ema.europa.eu
  11. Japanese prescribing information: injectable semaglutide for obesity, June 2026. pmda.go.jp
  12. Japanese patient medicine guide: injectable semaglutide for type 2 diabetes, March 2024. info.pmda.go.jp
  13. Japanese prescribing information: tirzepatide for obesity, September 2026. pmda.go.jp
  14. Japanese prescribing information: tirzepatide for type 2 diabetes. medical.lilly.com
  15. Japanese patient medicine guide: oral semaglutide for type 2 diabetes, March 2024. info.pmda.go.jp

Label sources last checked on October 30, 2026. Onederland summarizes them; your prescriber and the full prescribing information come first.

About dose steps

Do I have to reach the highest dose?

No. Labels list more than one maintenance dose for most medicines, and your prescriber chooses with you.

Why doesn’t this show my dates?

On purpose. A date would read like an instruction to move up, and that decision is for you and your prescriber.

Can I track my own dose steps?

Yes, in the Onederland app. It shows each dose you log and when a step changed, so you can share it at your next visit.

Published by Micktron LLC · Sources checked October 30, 2026

Keep activity and dose records in one free app

Download on the App StoreGet it on Google Play

Available for iPhone, iPad and Android: iOS 18+, iPadOS 18+ or Android 10+. Apple Health is for iPhone/iPad; Android uses Health Connect.

QR code that opens Onederland on the App StoreScan to get it on the App Store for iPhone
QR code that opens Onederland on Google PlayScan to get Onederland on Google Play for Android